製品: PEVR2 Antibody
カタログ: DF5142
タンパク質の説明: Rabbit polyclonal antibody to PEVR2
アプリケーション: WB IF/ICC
反応性: Human
分子量: 46 KD; 46kD(Calculated).
ユニプロット: Q9NWF4
RRID: AB_2837501

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
PEVR2 Antibody detects endogenous levels of total PEVR2.
RRID:
AB_2837501
引用形式: Affinity Biosciences Cat# DF5142, RRID:AB_2837501.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ10060; G protein coupled receptor 172B; GPCR; GPCR42; hRFT1; member 1; OTTHUMP00000125300; PAR2; PERV-A receptor 2; PERVA receptor 2; Porcine endogenous retrovirus A receptor 2; Protein GPR172B; Putative G protein coupled receptor GPCR42; Riboflavin transporter 1; riboflavin transporter; S52A1_HUMAN; SLC52A1; Solute carrier family 52; Solute carrier family 52, riboflavin transporter, member 1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NWF4 S52A1_HUMAN:

Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.

タンパク質配列:
MAAPTLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGKGEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPAPTNGTSGPPLDFPERFPASTFFWALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP

PTMs - Q9NWF4 基板として

Site PTM Type Enzyme
K245 Ubiquitination

研究背景

機能:

Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism. Humans are unable to synthesize vitamin B2/riboflavin and must obtain it via intestinal absorption.

(Microbial infection) May function as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.

タンパク質ファミリー:

Belongs to the riboflavin transporter family.

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