TAS2R8 Antibody - #DF5167
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF5167, RRID:AB_2837516.
折りたたみ／展開
T2R8; Taste receptor, family B, member 5; Taste receptor, type 2, member 8; TRB5;
免疫原
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
- Q9NYW2 TA2R8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKIPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYYISSILMTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQTFVRMLTCRKIACMI
PTMs - Q9NYW2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T43 | Phosphorylation | Uniprot | |
| Y46 | Phosphorylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| T301 | Phosphorylation | Uniprot |
研究背景
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Membrane>Multi-pass membrane protein.
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
Belongs to the G-protein coupled receptor T2R family.
研究領域
· Organismal Systems > Sensory system > Taste transduction.
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