MRGX3 Antibody - #DF5177

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製品: MRGX3 Antibody
カタログ: DF5177
タンパク質の説明: Rabbit polyclonal antibody to MRGX3
アプリケーション: WB IF/ICC
反応性: Human
分子量: 34 KD; 36kD(Calculated).
ユニプロット: Q96LB0
RRID: AB_2837526

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説明書
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WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
MRGX3 Antibody detects endogenous levels of total MRGX3.
RRID:
AB_2837526
引用形式: Affinity Biosciences Cat# DF5177, RRID:AB_2837526.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

G protein coupled receptor SNSR1; G protein coupled receptor SNSR2; G protein-coupled receptor MRGX 3; G protein-coupled receptor MRGX3; GPCR; Mas related GPCR member X3; Mas-related G protein coupled MRGX 3; Mas-related G protein coupled MRGX3; Mas-related G-protein coupled receptor member X3; MAS-related GPR, member X3; MRGPRX3; MRGX3; MRGX3_HUMAN; Sensory neuron-specific G-protein coupled receptor 1; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2;

免疫原

免疫原:
Uniprot:

Q96LB0(MRGX3_HUMAN) >>Visit HPA database.

遺伝子(ID):
MRGPRX3(117195)
発現特異性:
Q96LB0 MRGX3_HUMAN:

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

タンパク質配列:
MDSTIPVLGTELTPINGREETPCYKQTLSFTGLTCIVSLVALTGNAVVLWLLGCRMRRNAVSIYILNLVAADFLFLSGHIICSPLRLINIRHPISKILSPVMTFPYFIGLSMLSAISTERCLSILWPIWYHCRRPRYLSSVMCVLLWALSLLRSILEWMFCDFLFSGANSVWCETSDFITIAWLVFLCVVLCGSSLVLLVRILCGSRKMPLTRLYVTILLTVLVFLLCGLPFGIQWALFSRIHLDWKVLFCHVHLVSIFLSALNSSANPIIYFFVGSFRQRQNRQNLKLVLQRALQDTPEVDEGGGWLPQETLELSGSRLEQ

研究背景

機能:

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

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