PTGDR Antibody - #DF5213
| 製品: | PTGDR Antibody |
| カタログ: | DF5213 |
| タンパク質の説明: | Rabbit polyclonal antibody to PTGDR |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 分子量: | 40 KD; 40kD(Calculated). |
| ユニプロット: | Q13258 |
| RRID: | AB_2837562 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF5213, RRID:AB_2837562.
折りたたみ／展開
AS 1; AS1; ASRT 1; ASRT1; DP; MGC49004; OTTHUMP00000178986; PD2R_HUMAN; PGD receptor; PGD2 receptor; Prostaglandin D2 receptor (DP); Prostaglandin D2 receptor; Prostanoid DP receptor; Ptgdr;
免疫原
Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
- Q13258 PD2R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
PTMs - Q13258 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S254 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| T353 | Phosphorylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S358 | Phosphorylation | Uniprot |
研究背景
Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
Cell membrane>Multi-pass membrane protein.
Expressed in retinal choroid, ciliary epithelium, longitudinal and circular ciliary muscles, iris, small intestine and platelet membranes.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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