CD37 Antibody - #BF0228

(1)  
製品: CD37 Antibody
カタログ: BF0228
タンパク質の説明: Mouse monoclonal antibody to CD37
アプリケーション: IF/ICC ELISA
反応性: Human, Mouse
分子量: 31.7kDa; 32kD(Calculated).
ユニプロット: P11049
RRID: AB_2833693

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
ELISA 1:10000, IF/ICC 1:200-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Monoclonal [AFB1669]
特異性:
CD37 antibody detects endogenous levels of total CD37.
RRID:
AB_2833693
引用形式: Affinity Biosciences Cat# BF0228, RRID:AB_2833693.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CD 37; Cd37; CD37 antigen; CD37 molecule; CD37_HUMAN; Cell differentiation antigen 37; GP52 40; Leukocyte antigen CD37; Leukocyte surface antigen CD37; MGC120234; Tetraspanin 26; Tetraspanin-26; Tetraspanin26; TSPAN 26; Tspan-26; TSPAN26;

免疫原

免疫原:

Purified recombinant fragment of human CD37 expressed in E. Coli.

Uniprot:

P11049(CD37_HUMAN) >>Visit HPA database.

遺伝子(ID):
CD37(951)
発現特異性:
P11049 CD37_HUMAN:

B-lymphocytes.

タンパク質の説明:
CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
タンパク質配列:
MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLELGFMTLSIFLCRNLDHVYNRLARYR

研究背景

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

B-lymphocytes.

サブユニット構造:

Interacts with SCIMP.

タンパク質ファミリー:

Belongs to the tetraspanin (TM4SF) family.

研究領域

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

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