IL5 Antibody - #AF5123
(3)
(5)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF5123, RRID:AB_2837609.
折りたたみ／展開
B-cell differentiation factor I; Colony stimulating factor; EDF; Eosinophil differentiation factor; IL-5; IL5; IL5_HUMAN; Interleukin 5 (colony stimulating factor, eosinophil); Interleukin 5; Interleukin-5; T Cell Replacing Factor; T-cell replacing factor; TRF;
免疫原
- P05113 IL5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P05113 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T22 | O-Glycosylation | Uniprot | |
| N47 | N-Glycosylation | Uniprot | |
| T73 | Phosphorylation | Uniprot |
研究背景
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Secreted.
Homodimer; disulfide-linked.
Belongs to the IL-5 family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Immune diseases > Asthma.
· Human Diseases > Immune diseases > Autoimmune thyroid disease.
· Human Diseases > Immune diseases > Inflammatory bowel disease (IBD).
· Human Diseases > Immune diseases > Allograft rejection.
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
· Organismal Systems > Immune system > IL-17 signaling pathway. (View pathway)
· Organismal Systems > Immune system > Th1 and Th2 cell differentiation. (View pathway)
· Organismal Systems > Immune system > T cell receptor signaling pathway. (View pathway)
· Organismal Systems > Immune system > Fc epsilon RI signaling pathway. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
参考文献
Application: WB Species: Hu Sheep Sample: liver tissue
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