Heme oxygenase 2 Antibody - #AF5143
| 製品: | Heme oxygenase 2 Antibody |
| カタログ: | AF5143 |
| タンパク質の説明: | Rabbit polyclonal antibody to Heme oxygenase 2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Sheep, Dog |
| 分子量: | 36 kDa; 36kD(Calculated). |
| ユニプロット: | P30519 |
| RRID: | AB_2837629 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF5143, RRID:AB_2837629.
折りたたみ／展開
Heme oxygenase (decycling) 2; Heme oxygenase (decyclizing) 2; Heme oxygenase 2; HMOX 2; Hmox2; HMOX2 protein; HMOX2_HUMAN; HO 2; HO-2; HO2; OTTHUMP00000159847;
免疫原
- P30519 HMOX2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P30519 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| K38 | Ubiquitination | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| Y157 | Phosphorylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| Y202 | Phosphorylation | Uniprot | |
| K216 | Acetylation | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| Y268 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| C282 | S-Nitrosylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| S295 | Phosphorylation | Uniprot | |
| Y314 | Phosphorylation | Uniprot | |
| Y315 | Phosphorylation | Uniprot |
研究背景
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Microsome. Endoplasmic reticulum.
Belongs to the heme oxygenase family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Digestive system > Mineral absorption.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.