Cytokeratin 5 Antibody - #AF5479
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF5479, RRID:AB_2837961.
折りたたみ/展開
58 kDa cytokeratin; CK-5; CK5; Cytokeratin-5; Cytokeratin5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K2C5_HUMAN; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); Keratin 5; Keratin; keratin complex 2, basic, gene 5; keratin, type II cytoskeletal 5; Keratin-5; Keratin5; KRT 5; Krt5; KRT5A; type II cytoskeletal 5; Type-II keratin Kb5;
免疫原
- P13647 K2C5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P13647 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S2 | Phosphorylation | Uniprot | |
S5 | Phosphorylation | Uniprot | |
S8 | Phosphorylation | Uniprot | |
S11 | Phosphorylation | Uniprot | |
S14 | Phosphorylation | Uniprot | |
S16 | Phosphorylation | Uniprot | |
S18 | Phosphorylation | Uniprot | |
T19 | Phosphorylation | Uniprot | |
S21 | Phosphorylation | Uniprot | |
T24 | Phosphorylation | Uniprot | |
S26 | Phosphorylation | Uniprot | |
S28 | Phosphorylation | Uniprot | |
S31 | Phosphorylation | Uniprot | |
S36 | Phosphorylation | Uniprot | |
S38 | Phosphorylation | Uniprot | |
S50 | Phosphorylation | Uniprot | |
Y60 | Phosphorylation | Uniprot | |
S62 | Phosphorylation | Uniprot | |
S64 | Phosphorylation | Uniprot | |
Y66 | Phosphorylation | Uniprot | |
S71 | Phosphorylation | Uniprot | |
K72 | Acetylation | Uniprot | |
K72 | Methylation | Uniprot | |
S75 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
T78 | Phosphorylation | Uniprot | |
S82 | Phosphorylation | Uniprot | |
T151 | Phosphorylation | Uniprot | |
K173 | Ubiquitination | Uniprot | |
T174 | Phosphorylation | Uniprot | |
K178 | Acetylation | Uniprot | |
K178 | Methylation | Uniprot | |
K178 | Sumoylation | Uniprot | |
K178 | Ubiquitination | Uniprot | |
S181 | Phosphorylation | Uniprot | |
K185 | Acetylation | Uniprot | |
K185 | Ubiquitination | Uniprot | |
K199 | Methylation | Uniprot | |
Y222 | Phosphorylation | Uniprot | |
S242 | Phosphorylation | Uniprot | |
K257 | Methylation | Uniprot | |
K257 | Ubiquitination | Uniprot | |
Y258 | Phosphorylation | Uniprot | |
K264 | Methylation | Uniprot | |
K264 | Ubiquitination | Uniprot | |
Y283 | Phosphorylation | Uniprot | |
S337 | Phosphorylation | Uniprot | |
Y346 | Phosphorylation | Uniprot | |
S353 | Phosphorylation | Uniprot | |
T355 | Phosphorylation | Uniprot | |
S359 | Phosphorylation | Uniprot | |
Y361 | Phosphorylation | Uniprot | |
T363 | Phosphorylation | Uniprot | |
Y365 | Phosphorylation | Uniprot | |
K426 | Ubiquitination | Uniprot | |
K443 | Sumoylation | Uniprot | |
Y453 | Phosphorylation | Uniprot | |
R480 | Methylation | Uniprot | |
S567 | Phosphorylation | Uniprot | |
S571 | Phosphorylation | Uniprot | |
S574 | Phosphorylation | Uniprot | |
S579 | Phosphorylation | Uniprot | |
S587 | Phosphorylation | Uniprot | |
S590 | Phosphorylation | Uniprot |
研究背景
Heterodimer of a type I and a type II keratin. Heterodimer with type I keratin KRT25 leading to the formation of keratin intermediate filament (KIF) network. Heterodimer with KRT14. Interacts with TCHP. Interacts with EPPK1 (By similarity).
Belongs to the intermediate filament family.
参考文献
Application: IF/ICC Species: mouse Sample: thymic epithelial cells
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