Glycophorin C/GPC Antibody - #DF6364
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6364, RRID:AB_2838328.
折りたたみ／展開
CD236; CD236R; GE; GLPC; GLPC_HUMAN; Glycoconnectin; Glycophorin C (Gerbich blood group); Glycophorin D; Glycophorin-C; Glycophorin-D; Glycoprotein beta; GPC; GPD; Gypc; GYPD; MGC117309; MGC126191; MGC126192; PAS 2; PAS 2'; PAS-2''; Sialoglycoprotein D;
免疫原
Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
- P04921 GLPC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWSTRSPNSTAWPLSLEPDPGMASASTTMHTTTIAEPDPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKGTYHTNEAKGTEFAESADAALQGDPALQDAGDSSRKEYFI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P04921 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | O-Glycosylation | Uniprot | |
| T4 | O-Glycosylation | Uniprot | |
| S6 | O-Glycosylation | Uniprot | |
| N8 | N-Glycosylation | Uniprot | |
| S9 | O-Glycosylation | Uniprot | |
| T10 | O-Glycosylation | Uniprot | |
| S15 | O-Glycosylation | Uniprot | |
| S24 | O-Glycosylation | Uniprot | |
| S26 | O-Glycosylation | Uniprot | |
| T27 | O-Glycosylation | Uniprot | |
| T28 | O-Glycosylation | Uniprot | |
| T31 | O-Glycosylation | Uniprot | |
| T32 | O-Glycosylation | Uniprot | |
| T33 | O-Glycosylation | Uniprot | |
| S42 | O-Glycosylation | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| Y126 | Phosphorylation | Uniprot |
研究背景
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
O-glycosylated with core 1 or possibly core 8 glycans.
Cell membrane>Single-pass type III membrane protein.
Note: Linked to the membrane via band 4.1.
Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.
Belongs to the glycophorin-C family.
研究領域
· Human Diseases > Infectious diseases: Parasitic > Malaria.
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