CETP Antibody - #DF6394

(3)  
製品: CETP Antibody
カタログ: DF6394
タンパク質の説明: Rabbit polyclonal antibody to CETP
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
分子量: 55kDa; 55kD(Calculated).
ユニプロット: P11597
RRID: AB_2838357

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
CETP Antibody detects endogenous levels of total CETP.
RRID:
AB_2838357
引用形式: Affinity Biosciences Cat# DF6394, RRID:AB_2838357.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

BPIFF; CETP; CETP_HUMAN; Cholesteryl ester transfer protein; Cholesteryl ester transfer protein plasma; HDLCQ10; Lipid transfer protein I;

免疫原

免疫原:
Uniprot:

P11597(CETP_HUMAN) >>Visit HPA database.

遺伝子(ID):
CETP(1071)
発現特異性:
P11597 CETP_HUMAN:

Expressed by the liver and secreted in plasma.

タンパク質の説明:
Cholesteryl ester transfer protein (CETP) is a circulating metabolic enzyme that transports cholesterol from the arteries to the liver (1-3). CETP converts cholesteryl esters from antiatherogenic high density lipoproteins (HDLs) to proatherogenicapolipoprotein B (apoB)-containing lipoproteins, including very low-, intermediate-, and low-DLs (3). Efficient transfer and exchange of cholesteryl esters and triglycerides between the lipoprotein classes of human plasma is necessary to maintain healthy arteries (4,5).
タンパク質配列:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS

PTMs - P11597 基板として

Site PTM Type Enzyme
N105 N-Glycosylation
T113 Phosphorylation
N257 N-Glycosylation
S349 Phosphorylation
N358 N-Glycosylation
S400 Phosphorylation
T407 Phosphorylation

研究背景

機能:

Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination.

細胞の位置付け:

Secreted>Extracellular space.
Note: Secreted in plasma.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed by the liver and secreted in plasma.

タンパク質ファミリー:

Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

研究領域

· Organismal Systems > Digestive system > Cholesterol metabolism.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.