NAT1 Antibody - #DF6459
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6459, RRID:AB_2838421.
折りたたみ／展開
AAC1; ARY1_HUMAN; Arylamide acetylase 1; Arylamine N acetyltransferase 1; Arylamine N-acetyltransferase 1; mNAT; Monomorphic arylamine N acetyltransferase; Monomorphic arylamine N-acetyltransferase; N acetyltransferase type 1; N-acetyltransferase type 1; NAT 1; NAT-1; nat1; NATI;
免疫原
- P18440 ARY1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P18440 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| T25 | Phosphorylation | Uniprot | |
| Y101 | Phosphorylation | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| Y208 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| T227 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| K256 | Ubiquitination | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| S274 | Phosphorylation | Uniprot | |
| T289 | Phosphorylation | Uniprot |
研究背景
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Cytoplasm.
Belongs to the arylamine N-acetyltransferase family.
研究領域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Biosynthesis of other secondary metabolites > Caffeine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
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For Research Use Only.
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