SERPINC1 Antibody - #DF6470
| 製品: | SERPINC1 Antibody |
| カタログ: | DF6470 |
| タンパク質の説明: | Rabbit polyclonal antibody to SERPINC1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 53kDa; 53kD(Calculated). |
| ユニプロット: | P01008 |
| RRID: | AB_2838432 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6470, RRID:AB_2838432.
折りたたみ／展開
ANT3_HUMAN; Antithrombin; Antithrombin III; Antithrombin-III; AntithrombinIII; AT 3; AT III; AT3; AT3D; ATIII; Heparin cofactor I; MGC22579; Serine (or cysteine) proteinase inhibitor clade C (antithrombin) member 1; Serine cysteine proteinase inhibitor clade C member 1; Serine proteinase inhibitor clade C member 1; Serpin C1; Serpin family C member 1; Serpin peptidase inhibitor clade C (antithrombin) member 1; SERPINC1; THPH7;
免疫原
- P01008 ANT3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P01008 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T10 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| T63 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| N128 | N-Glycosylation | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| N187 | N-Glycosylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| N224 | N-Glycosylation | Uniprot | |
| Y272 | Phosphorylation | Uniprot |
研究背景
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
Phosphorylated by FAM20C in the extracellular medium.
Secreted>Extracellular space.
Found in plasma.
Forms protease inhibiting heterodimer with TMPRSS7.
Belongs to the serpin family.
研究領域
· Organismal Systems > Immune system > Complement and coagulation cascades. (View pathway)
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