KIR3DL1 Antibody - #DF6505
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6505, RRID:AB_2838467.
折りたたみ/展開
AMB11; CD158 antigen-like family member E; CD158e; CD158e antigen; CD158E1; CD158E1/2; CD158E2; CL11; CL2; HLA-BW4-specific inhibitory NK cell receptor; KI3L1_HUMAN; killer cell immunoglobulin like receptor; Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1; Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1; Killer cell immunoglobulin-like receptor 3DL1; KIR; KIR antigen 3DL1; KIR G1; Kir3dl1; KIR3DS1; Kirl1; Kirl2; Krl1; MGC119726; MGC119728; MGC126589; MGC126591; MHC class I NK cell receptor; Natural killer associated transcript 3; Natural killer cell inhibitory receptor; Natural killer-associated transcript 3; NK receptor; NK-associated transcript 10; NK-associated transcript 3; NK-associated transcript 3delIg1; NKAT-3; NKAT10; NKAT3; NKB1; NKB1B; p70 killer cell inhibitory receptor; p70 natural killer cell receptor clones CL 2/CL 11; p70 natural killer cell receptor clones CL-2/CL-11; p70 NK receptor CL-2/CL-11;
免疫原
- P43629 KI3L1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPSSKSGNPRHLHILIGTSVVIILFILLLFFLLHLWCSNKKNAAVMDQEPAGNRTANSEDSDEQDPEEVTYAQLDHCVFTQRKITRPSQRPKTPPTDTILYTELPNAKPRSKVVSCP
PTMs - P43629 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
N92 | N-Glycosylation | Uniprot | |
N179 | N-Glycosylation | Uniprot | |
K223 | Sumoylation | Uniprot | |
S246 | Phosphorylation | Uniprot | |
N273 | N-Glycosylation | Uniprot | |
S385 | Phosphorylation | P48730 (CSNK1D) , P68400 (CSNK2A1) | Uniprot |
S388 | Phosphorylation | P48730 (CSNK1D) , P68400 (CSNK2A1) | Uniprot |
S415 | Phosphorylation | P05771-2 (PRKCB) , P17252 (PRKCA) , Q02156 (PRKCE) , P05129 (PRKCG) | Uniprot |
T420 | Phosphorylation | Uniprot |
研究背景
Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
Cell membrane>Single-pass type I membrane protein.
Ig-like C2-type domain 2 mediates specificity through recognition of the Bw4 epitope.
Belongs to the immunoglobulin superfamily.
研究領域
· Human Diseases > Immune diseases > Graft-versus-host disease.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
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