KIR2DL3 Antibody - #DF6561
製品: | KIR2DL3 Antibody |
カタログ: | DF6561 |
タンパク質の説明: | Rabbit polyclonal antibody to KIR2DL3 |
アプリケーション: | WB IF/ICC |
反応性: | Human |
分子量: | 38kDa; 38kD(Calculated). |
ユニプロット: | P43628 |
RRID: | AB_2838523 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6561, RRID:AB_2838523.
折りたたみ/展開
CD158 antigen like family member B2; CD158 antigen-like family member B2; CD158b; CD158b2; GL183; KI2L3_HUMAN; Killer cell immunoglobulin like receptor two domains long cytoplasmic tail 3; Killer cell immunoglobulin-like receptor 2DL3; Killer inhibitory receptor cl 2-3; Killer inhibitory receptor CL2 3; KIR 023GB; KIR-023GB; KIR-K7b; KIR-K7c; KIR023GB; KIR2DL3; KIR2DS5; KIRCL23; MHC class I NK cell receptor; Natural killer associated transcript 2; Natural killer cell inhibitory receptor KIR2DL3; Natural killer-associated transcript 2; NKAT; NKAT-2; NKAT2; NKAT2a; NKAT2b; p58; p58 natural killer cell receptor clone CL 6; p58 natural killer cell receptor clone CL-6; p58 NK Receptor; p58 NK receptor CL 6; p58 NK receptor CL-6; p58.2 MHC class I specific NK receptor; p58.2 MHC class-I-specific NK receptor;
免疫原
- P43628 KI2L3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLMVVSMVCVGFFLLQGAWPHEGVHRKPSLLAHPGPLVKSEETVILQCWSDVRFQHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHERRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSETGNPRHLHVLIGTSVVIILFILLLFFLLHRWCCNKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDIIVYTELPNAEP
PTMs - P43628 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S41 | Phosphorylation | Uniprot | |
T44 | Phosphorylation | Uniprot | |
S51 | Phosphorylation | Uniprot | |
S86 | Phosphorylation | Uniprot | |
Y98 | Phosphorylation | Uniprot | |
T180 | Phosphorylation | Uniprot |
研究背景
Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.
Cell membrane>Single-pass type I membrane protein.
Interacts with ARRB2.
Belongs to the immunoglobulin superfamily.
研究領域
· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)
· Human Diseases > Immune diseases > Graft-versus-host disease.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
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