FCER1A Antibody - #DF6593
(1)
(5)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6593, RRID:AB_2838555.
折りたたみ／展開
Fc epsilon RI alpha; Fc epsilon RI alpha chain; Fc epsilon RI alpha-chain; Fc fragment of IgE high affinity I receptor for alpha polypeptide; Fc fragment of IgE, high affinity I, receptor for, alpha subunit; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor alpha polypeptide; Fc IgE receptor, alpha chain; Fc IgE receptor, alpha polypeptide; Fc of IgE high affinity I receptor for alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER 1A; Fcer1a; FCERA_HUMAN; FceRI alpha; FcERI; high affinity IgE receptor; High affinity immunoglobulin epsilon receptor alpha subunit; high affinity immunoglobulin epsilon receptor alpha-subunit; High affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor alpha subunit; IgE Fc receptor subunit alpha; Immunoglobulin E receptor high affinity of mast cells alpha polypeptide; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide;
免疫原
- P12319 FCERA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTRKGFRLLNPHPKPNPKNN
PTMs - P12319 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N46 | N-Glycosylation | Uniprot | |
| N67 | N-Glycosylation | Uniprot | |
| N99 | N-Glycosylation | Uniprot | |
| N165 | N-Glycosylation | Uniprot | |
| N191 | N-Glycosylation | Uniprot | |
| K241 | Acetylation | Uniprot | |
| K251 | Acetylation | Uniprot |
研究背景
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Cell membrane>Single-pass type I membrane protein.
Tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains.
研究領域
· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway. (View pathway)
· Human Diseases > Immune diseases > Asthma.
· Organismal Systems > Immune system > Fc epsilon RI signaling pathway. (View pathway)
参考文献
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