POLR2I Antibody - #DF6668
| 製品: | POLR2I Antibody |
| カタログ: | DF6668 |
| タンパク質の説明: | Rabbit polyclonal antibody to POLR2I |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 15kDa; 15kD(Calculated). |
| ユニプロット: | P36954 |
| RRID: | AB_2838630 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6668, RRID:AB_2838630.
折りたたみ／展開
DNA directed RNA polymerase II 14.5 kDa polypeptide; DNA directed RNA polymerase II polypeptide I; DNA directed RNA polymerase II subunit I; DNA directed RNA polymerase II subunit RPB9; DNA-directed RNA polymerase II subunit I; DNA-directed RNA polymerase II subunit RPB9; hRPB14.5; POLR2I; Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa; RNA polymerase II 14.5 kDa subunit; RNA polymerase II subunit B9; RPB14.5; RPB9; RPB9_HUMAN;
免疫原
- P36954 RPB9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEPDGTYEPGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P36954 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K27 | Ubiquitination | Uniprot | |
| Y37 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| Y54 | Phosphorylation | Uniprot | |
| T59 | Phosphorylation | Uniprot | |
| T66 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| T81 | Phosphorylation | Uniprot |
研究背景
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity).
Nucleus>Nucleolus.
Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
研究領域
· Genetic Information Processing > Transcription > RNA polymerase.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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