SLC25A4 Antibody - #DF6674
| 製品: | SLC25A4 Antibody |
| カタログ: | DF6674 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC25A4 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 33kDa; 33kD(Calculated). |
| ユニプロット: | P12235 |
| RRID: | AB_2838636 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6674, RRID:AB_2838636.
折りたたみ／展開
AAC1; Adenine nucleotide translocator 1 (skeletal muscle); Adenine nucleotide translocator 1; ADP; ADP ATP carrier protein 1; ADP ATP carrier protein heart/skeletal muscle isoform T1; ADP/ATP translocase 1; ADT1_HUMAN; ANT 1; ANT; ANT1; ATP carrier protein 1; ATP carrier protein; heart/skeletal muscle isoform T1; PEO2; PEO3; SLC25A4; Solute carrier family 25 member 4; T1;
免疫原
- P12235 ADT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGDHAWSFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P12235 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| K10 | Acetylation | Uniprot | |
| S22 | Phosphorylation | Uniprot | |
| K23 | Acetylation | Uniprot | |
| T24 | Phosphorylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K33 | Ubiquitination | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K43 | Acetylation | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K52 | Acetylation | Uniprot | |
| K52 | Methylation | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| Y81 | Phosphorylation | Uniprot | |
| T84 | Phosphorylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| K94 | Acetylation | Uniprot | |
| K96 | Acetylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| T139 | Phosphorylation | Uniprot | |
| R140 | Methylation | Uniprot | |
| K147 | Methylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| K166 | Acetylation | Uniprot | |
| S167 | Phosphorylation | Uniprot | |
| Y174 | Phosphorylation | Uniprot | |
| Y187 | Phosphorylation | Uniprot | |
| Y191 | Phosphorylation | Uniprot | |
| Y195 | Phosphorylation | P06239 (LCK) , P12931 (SRC) | Uniprot |
| T197 | Phosphorylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| K245 | Ubiquitination | Uniprot | |
| K272 | Acetylation | Uniprot | |
| K272 | Methylation | Uniprot | |
| K272 | Ubiquitination | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| K295 | Acetylation | Uniprot | |
| K295 | Ubiquitination | Uniprot |
研究背景
Involved in mitochondrial ADP/ATP transport. Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.
Mitochondrion inner membrane>Multi-pass membrane protein.
Found in a complex with ARL2, ARL2BP and SLC25A4. Interacts with ARL2BP (By similarity). Homodimer.
(Microbial infection) Interacts with HIV-1 Vpr.
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
Belongs to the mitochondrial carrier (TC 2.A.29) family.
研究領域
· Cellular Processes > Cell growth and death > Necroptosis. (View pathway)
· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
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