EBAG9 Antibody - #DF6703
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6703, RRID:AB_2838665.
折りたたみ／展開
BAG9; Cancer associated surface antigen; Cancer associated surface antigen RCAS1; Cancer-associated surface antigen RCAS1; EB9; EBAG 9; EBAG9; Estrogen receptor binding fragment associated gene 9 protein; Estrogen receptor binding site associated antigen 9; estrogen receptor binding site associated, antigen, 9; Estrogen receptor-binding fragment-associated gene 9 protein; PDAF; RCAS 1; RCAS1; RCAS1_HUMAN; Receptor binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells;
免疫原
Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
- O00559 RCAS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAITQFRLFKFCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSELGDLDTWQENTNAWEEEEDAAWQAEEVLRQQKLADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00559 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S36 | Phosphorylation | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| S50 | Phosphorylation | Uniprot | |
| S62 | Phosphorylation | Uniprot | |
| T82 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| T101 | Phosphorylation | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| T134 | Phosphorylation | Uniprot | |
| K202 | Acetylation | Uniprot |
研究背景
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
Golgi apparatus membrane>Single-pass type III membrane protein.
Note: According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain.
Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
Homodimer.
The coiled coil domain is necessary for the homodimerization.
研究領域
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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