CDA Antibody - #DF6749
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6749, RRID:AB_2838711.
折りたたみ／展開
CDD; Cytidine aminohydrolase; Cytidine deaminase; EC 3.5.4.5;
免疫原
Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.
- P32320 CDD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P32320 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K11 | Acetylation | Uniprot | |
| K11 | Ubiquitination | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| Y79 | Phosphorylation | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| S136 | Phosphorylation | Uniprot |
研究背景
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.
Homotetramer.
Belongs to the cytidine and deoxycytidylate deaminase family.
研究領域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
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