EPHX1 Antibody - #DF6799
| 製品: | EPHX1 Antibody |
| カタログ: | DF6799 |
| タンパク質の説明: | Rabbit polyclonal antibody to EPHX1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 53kDa; 53kD(Calculated). |
| ユニプロット: | P07099 |
| RRID: | AB_2838761 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6799, RRID:AB_2838761.
折りたたみ／展開
EPHX 1; EPHX; Ephx1; EPOX; Epoxide hydratase; Epoxide hydrolase 1; Epoxide hydrolase 1 microsomal (xenobiotic); Epoxide hydroxylase 1; Epoxide hydroxylase 1 microsomal (xenobiotic); HYEP_HUMAN; HYL1; MEH; Microsomal epoxide hydrolase;
免疫原
- P07099 HYEP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEIHDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKIEGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEVICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVPSHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYMHIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVMLYWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKLISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P07099 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S47 | Phosphorylation | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| T55 | Phosphorylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K92 | Ubiquitination | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K117 | Methylation | Uniprot | |
| K119 | Methylation | Uniprot | |
| K131 | Acetylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| K210 | Acetylation | Uniprot | |
| Y283 | Phosphorylation | Uniprot | |
| K286 | Ubiquitination | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| Y291 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| Y339 | Phosphorylation | Uniprot | |
| Y361 | Phosphorylation | Uniprot | |
| K386 | Acetylation | Uniprot | |
| K386 | Ubiquitination | Uniprot | |
| Y393 | Phosphorylation | Uniprot | |
| T408 | Phosphorylation | Uniprot | |
| S422 | Phosphorylation | Uniprot | |
| Y423 | Phosphorylation | Uniprot | |
| Y425 | Phosphorylation | Uniprot | |
| S450 | Phosphorylation | Uniprot |
研究背景
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids.
Microsome membrane>Single-pass type III membrane protein. Endoplasmic reticulum membrane>Single-pass type III membrane protein.
Found in liver.
Belongs to the peptidase S33 family.
研究領域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
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