PPA1 Antibody - #DF6832
(3)
| 製品: | PPA1 Antibody |
| カタログ: | DF6832 |
| タンパク質の説明: | Rabbit polyclonal antibody to PPA1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 33kDa; 33kD(Calculated). |
| ユニプロット: | Q15181 |
| RRID: | AB_2838791 |
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse,Rat
予測:
Pig(92%), Bovine(100%), Horse(92%), Sheep(100%), Rabbit(100%), Dog(92%), Chicken(91%)
クローナリティ:
Polyclonal
特異性:
PPA1 Antibody detects endogenous levels of total PPA1.
RRID:
AB_2838791
引用形式: Affinity Biosciences Cat# DF6832, RRID:AB_2838791.
引用形式: Affinity Biosciences Cat# DF6832, RRID:AB_2838791.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
cytosolic inorganic pyrophosphatase; diphosphate phosphohydrolase; inorganic diphosphatase; inorganic pyrophosphatase 1; Inorganic pyrophosphatase; IOPPP; IPYR_HUMAN; PP; PP1; PPA1; PPase; Pyp; pyrophosphatase, inorganic, 1; Pyrophosphate phospho hydrolase; Pyrophosphate phospho-hydrolase; SID6-8061;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
PPA1(Inorganic pyrophosphatase) is also named as IOPPP, PP and PPase. It maintains the thermodynamic favorability of these reactions by catalyzing the hydrolysis of pyrophosphates into organic phosphates, which are then exported across the cell membrane(PMID:16300924).The erythrocyte inorganic pyrophosphatase molecule would appear to be a dimer(PMID:4130389).This antibody is specific to PPA1.
タンパク質配列:
- Q15181 IPYR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
92
Horse
92
Dog
92
Chicken
91
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15181 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| T6 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| Y17 | Phosphorylation | Uniprot | |
| K22 | Ubiquitination | Uniprot | |
| K25 | Acetylation | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| Y28 | Phosphorylation | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| Y38 | Phosphorylation | Uniprot | |
| K57 | Acetylation | Uniprot | |
| K63 | Acetylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K70 | Acetylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| K74 | Acetylation | Uniprot | |
| K75 | Acetylation | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| R132 | Methylation | Uniprot | |
| K155 | Acetylation | Uniprot | |
| K176 | Acetylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K179 | Ubiquitination | Uniprot | |
| Y182 | Phosphorylation | Uniprot | |
| T186 | Phosphorylation | Uniprot | |
| Y193 | Phosphorylation | Uniprot | |
| K194 | Acetylation | Uniprot | |
| K199 | Acetylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K228 | Acetylation | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| T235 | Phosphorylation | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| T246 | Phosphorylation | Uniprot | |
| S248 | Phosphorylation | Uniprot | |
| S250 | Phosphorylation | Uniprot | |
| K253 | Acetylation | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| C270 | S-Nitrosylation | Uniprot | |
| C274 | S-Nitrosylation | Uniprot | |
| K282 | Ubiquitination | Uniprot |
研究背景
細胞の位置付け:
Cytoplasm.
組織特異性:
Expressed ubiquitously.
サブユニット構造:
Homodimer.
タンパク質ファミリー:
Belongs to the PPase family.
研究領域
· Metabolism > Energy metabolism > Oxidative phosphorylation.
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