UAP1 Antibody - #DF6843
| 製品: | UAP1 Antibody |
| カタログ: | DF6843 |
| タンパク質の説明: | Rabbit polyclonal antibody to UAP1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 57kDa; 59kD(Calculated). |
| ユニプロット: | Q16222 |
| RRID: | AB_2838802 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6843, RRID:AB_2838802.
折りたたみ／展開
AGX 1; AGX; AGX-1; AGX-2; AGX1; Antigen X; AntigenX; SPAG 2; SPAG2; Sperm associated antigen 2; Sperm-associated antigen 2; UAP 1; uap1; UAP1_HUMAN; UDP N acetylhexosamine pyrophosphorylase; UDP N acteylglucosamine pyrophosphorylase 1; UDP-N-acetylglucosamine pyrophosphorylase;
免疫原
Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
- Q16222 UAP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q16222 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K7 | Ubiquitination | Uniprot | |
| K12 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K122 | Ubiquitination | Uniprot | |
| Y125 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K145 | Ubiquitination | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| Y153 | Phosphorylation | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| K175 | Ubiquitination | Uniprot | |
| K180 | Acetylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K182 | Acetylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| K188 | Ubiquitination | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K278 | Ubiquitination | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| C293 | S-Nitrosylation | Uniprot | |
| Y299 | Phosphorylation | Uniprot | |
| Y304 | Phosphorylation | Uniprot | |
| K314 | Ubiquitination | Uniprot | |
| K356 | Ubiquitination | Uniprot | |
| K357 | Ubiquitination | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| T363 | Phosphorylation | Uniprot | |
| K369 | Ubiquitination | Uniprot | |
| K372 | Ubiquitination | Uniprot | |
| K377 | Ubiquitination | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| K390 | Ubiquitination | Uniprot | |
| K391 | Ubiquitination | Uniprot | |
| S404 | Phosphorylation | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| K472 | Acetylation | Uniprot | |
| K472 | Ubiquitination | Uniprot | |
| K519 | Ubiquitination | Uniprot |
研究背景
Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
Cytoplasm.
Note: In spermatozoa, localized to the principal piece of the tail, the neck region of the head and to a lesser extent, the midpiece of the tail.
Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver.
Monomer and homodimer. Isoform AGX1 is a homodimer. Isoform AGX2 is a monomer.
Belongs to the UDPGP type 1 family.
研究領域
· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.