LETMD1 Antibody - #DF6870
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6870, RRID:AB_2838829.
折りたたみ／展開
1110019O13Rik; Cervical cancer 1 proto oncogene protein; Cervical cancer proto oncogene 2 protein; DKFZp586A011; HCCR 2; HCCR1; HCCR2; HCRR 2; HCRR2; LETM1 domain containing 1; Regulator of TP53;
免疫原
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.
- Q6P1Q0 LTMD1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQTDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYLGTRR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6P1Q0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S48 | Phosphorylation | Uniprot | |
| K50 | Ubiquitination | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K107 | Ubiquitination | Uniprot | |
| Y183 | Phosphorylation | Uniprot | |
| T264 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K292 | Ubiquitination | Uniprot | |
| K304 | Ubiquitination | Uniprot |
研究背景
Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
Mitochondrion outer membrane>Single-pass membrane protein.
Kidney, liver, skeletal muscle, heart and brain. Overexpressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix.
Interacts with BRI3BP.
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