EEF1D Antibody - #DF6974
製品: | EEF1D Antibody |
カタログ: | DF6974 |
タンパク質の説明: | Rabbit polyclonal antibody to EEF1D |
アプリケーション: | WB IHC |
反応性: | Human, Mouse, Rat, Monkey |
予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 31kDa,37kDa; 31kD(Calculated). |
ユニプロット: | P29692 |
RRID: | AB_2838930 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6974, RRID:AB_2838930.
折りたたみ/展開
Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); Eukaryotic translation elongation factor 1 delta; FP1047; Guanine nucleotide exchange protein;
免疫原
- P29692 EF1D_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATNFLAHEKIWFDKFKYDDAERRFYEQMNGPVAGASRQENGASVILRDIARARENIQKSLAGSSGPGASSGTSGDHGELVVRIASLEVENQSLRGVVQELQQAISKLEARLNVLEKSSPGHRATAPQTQHVSPMRQVEPPAKKPATPAEDDEDDDIDLFGSDNEEEDKEAAQLREERLRQYAEKKAKKPALVAKSSILLDVKPWDDETDMAQLEACVRSIQLDGLVWGASKLVPVGYGIRKLQIQCVVEDDKVGTDLLEEEITKFEEHVQSVDIAAFNKI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P29692 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
A2 | Acetylation | Uniprot | |
K10 | Acetylation | Uniprot | |
K10 | Ubiquitination | Uniprot | |
K15 | Acetylation | Uniprot | |
K15 | Ubiquitination | Uniprot | |
K17 | Acetylation | Uniprot | |
K17 | Ubiquitination | Uniprot | |
Y18 | Phosphorylation | Uniprot | |
R24 | Methylation | Uniprot | |
Y26 | Phosphorylation | Uniprot | |
S37 | Phosphorylation | Uniprot | |
S44 | Phosphorylation | Uniprot | |
K59 | Ubiquitination | Uniprot | |
S60 | Phosphorylation | Uniprot | |
S64 | Phosphorylation | Uniprot | |
S65 | Phosphorylation | Uniprot | |
S70 | Phosphorylation | Uniprot | |
T73 | Phosphorylation | Uniprot | |
S74 | Phosphorylation | Uniprot | |
S86 | Phosphorylation | Uniprot | |
S93 | Phosphorylation | Uniprot | |
R95 | Methylation | Uniprot | |
S106 | Phosphorylation | Uniprot | |
K107 | Acetylation | Uniprot | |
K107 | Ubiquitination | Uniprot | |
K117 | Acetylation | Uniprot | |
K117 | Ubiquitination | Uniprot | |
S118 | Phosphorylation | Uniprot | |
S119 | Phosphorylation | Uniprot | |
T125 | Phosphorylation | Uniprot | |
T129 | Phosphorylation | Uniprot | |
S133 | Phosphorylation | P06493 (CDK1) | Uniprot |
T147 | Phosphorylation | Uniprot | |
S162 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
K169 | Ubiquitination | Uniprot | |
R178 | Methylation | Uniprot | |
Y182 | Phosphorylation | Uniprot | |
K185 | Ubiquitination | Uniprot | |
K186 | Ubiquitination | Uniprot | |
K188 | Ubiquitination | Uniprot | |
K189 | Ubiquitination | Uniprot | |
S197 | Phosphorylation | Uniprot | |
K203 | Acetylation | Uniprot | |
K203 | Sumoylation | Uniprot | |
S220 | Phosphorylation | Uniprot | |
S231 | Phosphorylation | Uniprot | |
K232 | Ubiquitination | Uniprot | |
Y238 | Phosphorylation | Uniprot | |
K242 | Ubiquitination | Uniprot | |
K265 | Ubiquitination | Uniprot | |
K280 | Ubiquitination | Uniprot |
研究背景
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.
Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
Nucleus.
Isoform 2 is specifically expressed in brain, cerebellum and testis.
EF-1 is composed of 4 subunits: alpha, beta, delta isoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2.
Belongs to the EF-1-beta/EF-1-delta family.
研究領域
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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