LHB Antibody - #DF7140

(3)  
製品: LHB Antibody
カタログ: DF7140
タンパク質の説明: Rabbit polyclonal antibody to LHB
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 15kD; 15kD(Calculated).
ユニプロット: P01229
RRID: AB_2839094

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
LHB Antibody detects endogenous levels of total LHB.
RRID:
AB_2839094
引用形式: Affinity Biosciences Cat# DF7140, RRID:AB_2839094.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CGB4; CHORIONIC GONADOTROPIN, BETA POLYPEPTIDE 4; hLHB; Interstitial cell stimulating hormone beta chain; Leutropin; LH-B; LHB; LSH beta; LSH-B; LSH-beta; LSHB; LSHB_HUMAN; Luteinizing hormone beta polypeptide; Luteinizing hormone subunit beta; Lutropin beta chain; Lutropin subunit beta;

免疫原

免疫原:
Uniprot:

P01229(LSHB_HUMAN) >>Visit HPA database.

遺伝子(ID):
LHB(3972)
発現特異性:
P01229 LSHB_HUMAN:

Pituitary gland.

タンパク質の説明:
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
タンパク質配列:
MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLLFL

研究背景

機能:

Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Pituitary gland.

サブユニット構造:

Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

タンパク質ファミリー:

Belongs to the glycoprotein hormones subunit beta family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Organismal Systems > Endocrine system > Ovarian steroidogenesis.

· Organismal Systems > Endocrine system > Prolactin signaling pathway.   (View pathway)

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