PSMD7 Antibody - #DF7297
| 製品: | PSMD7 Antibody |
| カタログ: | DF7297 |
| タンパク質の説明: | Rabbit polyclonal antibody to PSMD7 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 37kDa; 37kD(Calculated). |
| ユニプロット: | P51665 |
| RRID: | AB_2839236 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7297, RRID:AB_2839236.
折りたたみ／展開
26S proteasome non ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; integration site gene, mouse, homolog of; Moloney leukemia virus 34 proviral; Moloney leukemia virus 34 proviral integration; MOV34; Mov34 homolog; Mov34 protein homolog; MOV34L; P40; Proteasome (prosome, macropain) 26S subunit, non ATPase 7; Proteasome (prosome, macropain) 26S subunit, non ATPase, 7 (Mov34 homolog); Proteasome 26S S12; Proteasome 26S subunit, no-ATPase, 7; Proteasome subunit p40; PSD7_HUMAN; PSMD 7; PSMD7; Rpn8; S12;
免疫原
- P51665 PSMD7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P51665 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K28 | Ubiquitination | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| T149 | Phosphorylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| T186 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| K204 | Acetylation | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| R209 | Methylation | Uniprot | |
| K214 | Acetylation | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| S268 | Phosphorylation | Uniprot | |
| K279 | Acetylation | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| K304 | Ubiquitination | Uniprot | |
| K308 | Acetylation | Uniprot | |
| K310 | Acetylation | Uniprot |
研究背景
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD7, a base containing 6 ATPases and few additional components. Within the complex, PSMD7 interacts with subunit PSMD4 through their respective MPN domain. Interacts with TRIM5.
Belongs to the peptidase M67A family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Proteasome.
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
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