製品: MPG Antibody
カタログ: DF7328
タンパク質の説明: Rabbit polyclonal antibody to MPG
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 32kDa; 33kD(Calculated).
ユニプロット: P29372
RRID: AB_2839266

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(92%), Sheep(100%), Rabbit(83%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
MPG Antibody detects endogenous levels of total MPG.
RRID:
AB_2839266
引用形式: Affinity Biosciences Cat# DF7328, RRID:AB_2839266.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

3 alkyladenine DNA glycosylase; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; 3MG_HUMAN; AAG; ADPG; Alkyladenine DNA glycosylase; anpg; APNG; CRA36.1; DNA 3 methyladenine glycosylase; DNA-3-methyladenine glycosylase; MDG; Mid1; Mpg; N methylpurine DNA glycosirase; N methylpurine DNA glycosylase; N-methylpurine-DNA glycosylase; PIG11; PIG16; Proliferation inducing protein 11; Proliferation inducing protein 16;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MVTPALQMKKPKQFCRRMGQKKQRPARAGQPHSSSDAAQAPAEQPHSSSDAAQAPCPRERCLGPPTTPGPYRSIYFSSPKGHLTRLGLEFFDQPAVPLARAFLGQVLVRRLPNGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYIIYGMYFCMNISSQGDGACVLLRALEPLEGLETMRQLRSTLRKGTASRVLKDRELCSGPSKLCQALAINKSFDQRDLAQDEAVWLERGPLEPSEPAVVAAARVGVGHAGEWARKPLRFYVRGSPWVSVVDRVAEQDTQA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Horse
92
Rabbit
83
Chicken
58
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P29372 基板として

Site PTM Type Enzyme
T66 Phosphorylation
T67 Phosphorylation
Y71 Phosphorylation
S73 Phosphorylation
Y75 Phosphorylation
S78 Phosphorylation
K80 Ubiquitination
T115 Phosphorylation
S137 Phosphorylation
K210 Ubiquitination
K229 Ubiquitination
S252 Phosphorylation
Y278 Phosphorylation

研究背景

機能:

Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

細胞の位置付け:

Cytoplasm. Mitochondrion matrix>Mitochondrion nucleoid. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Binds MBD1. Binds SSBP1.

タンパク質ファミリー:

Belongs to the DNA glycosylase MPG family.

研究領域

· Genetic Information Processing > Replication and repair > Base excision repair.

Restrictive clause

 

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