SERPINB3 Antibody - #DF7335
| 製品: | SERPINB3 Antibody |
| カタログ: | DF7335 |
| タンパク質の説明: | Rabbit polyclonal antibody to SERPINB3 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 分子量: | 44kDa; 45kD(Calculated). |
| ユニプロット: | P29508 |
| RRID: | AB_2839273 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7335, RRID:AB_2839273.
折りたたみ／展開
HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA; SCCA PD; SCCA-1; SCCA-PD; SCCA1; SCCAPD; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 3; Serpin B3; Serpin peptidase inhibitor clade B (ovalbumin) member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4-A; T4A;
免疫原
- P29508 SPB3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP
PTMs - P29508 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T35 | Phosphorylation | Uniprot | |
| Y73 | Phosphorylation | Uniprot | |
| Y119 | Phosphorylation | Uniprot | |
| T129 | Phosphorylation | Uniprot | |
| S149 | Phosphorylation | Uniprot | |
| S153 | Phosphorylation | Uniprot | |
| Y181 | Phosphorylation | Uniprot | |
| T206 | Phosphorylation | Uniprot | |
| K208 | Acetylation | Uniprot | |
| Y216 | Phosphorylation | Uniprot | |
| Y384 | Phosphorylation | Uniprot |
研究背景
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Cytoplasm.
Note: Seems to also be secreted in plasma by cancerous cells but at a low level.
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
Interacts with MAPK8/JNK1.
Belongs to the serpin family. Ov-serpin subfamily.
研究領域
· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.
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