RFC4 Antibody - #DF7367
| 製品: | RFC4 Antibody |
| カタログ: | DF7367 |
| タンパク質の説明: | Rabbit polyclonal antibody to RFC4 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat, Monkey |
| 予測: | Pig, Bovine, Horse, Rabbit, Dog, Xenopus |
| 分子量: | 39kDa; 40kD(Calculated). |
| ユニプロット: | P35249 |
| RRID: | AB_2839305 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7367, RRID:AB_2839305.
折りたたみ／展開
A1 37; A1 37 kDa subunit; Activator 1 37; Activator 1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37; Replication factor C 37 kDa subunit; Replication factor C subunit 4; Replication factor C4; RF-C 37 kDa subunit; RFC 37; RFC37; RFC4 replication factor C (activator 1)4 37kDa; RfC4; RFC4_HUMAN;
免疫原
- P35249 RFC4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQKSIITEKLAEVDKCLADGADEHLQLISLCATVMQQLSQNC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35249 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K6 | Acetylation | Uniprot | |
| K6 | Methylation | Uniprot | |
| K6 | Ubiquitination | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| S11 | Phosphorylation | Uniprot | |
| T12 | Phosphorylation | Uniprot | |
| K13 | Acetylation | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| T17 | Phosphorylation | Uniprot | |
| K18 | Ubiquitination | Uniprot | |
| R20 | Methylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K43 | Ubiquitination | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| R114 | Methylation | Uniprot | |
| K124 | Ubiquitination | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| T166 | Phosphorylation | Uniprot | |
| T174 | Phosphorylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| T191 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| K200 | Ubiquitination | Uniprot | |
| K205 | Ubiquitination | Uniprot | |
| K216 | Acetylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| K217 | Acetylation | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| K255 | Ubiquitination | Uniprot | |
| K260 | Ubiquitination | Uniprot | |
| S285 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K294 | Ubiquitination | Uniprot | |
| K322 | Ubiquitination | Uniprot | |
| K324 | Ubiquitination | Uniprot | |
| K330 | Ubiquitination | Uniprot |
研究背景
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
Nucleus.
Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex either with RFC1 or with RAD17. The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated by PCNA.
Belongs to the activator 1 small subunits family.
研究領域
· Genetic Information Processing > Replication and repair > DNA replication.
· Genetic Information Processing > Replication and repair > Nucleotide excision repair.
· Genetic Information Processing > Replication and repair > Mismatch repair.
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