SULT2A1 Antibody - #DF7371
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7371, RRID:AB_2839309.
折りたたみ／展開
Alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotranasferase 2A1; Bile salt sulfotransferase; Dehydroepiandrosterone sulfotransferase; DHEA ST; DHEA sulfotranasferase; DHEA-ST; DHEAS; EC 2.8.2.14; Hst; hSTa; Hydroxysteroid sulfotransferase; ST2; ST2A1; ST2A1_HUMAN; ST2A3; STD; sulfotranasferase, dehydroepiandrosterone-preferring; Sulfotransferase 2A1; Sulfotransferase family 2A, dehydroepiandrosterone-preferring, member 1; Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1; Sult2a1;
免疫原
Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.
- Q06520 ST2A1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q06520 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S20 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| K135 | Acetylation | Uniprot | |
| K177 | Acetylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| Y184 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot | |
| S251 | Phosphorylation | Uniprot |
研究背景
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.
The N-terminus is blocked.
Cytoplasm.
Liver, adrenal and at lower level in the kidney. Is present in human fetus in higher level in the adrenal than the liver and the kidney.
Homodimer.
Belongs to the sulfotransferase 1 family.
研究領域
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
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