PGRMC1 Antibody - #DF7422
| 製品: | PGRMC1 Antibody |
| カタログ: | DF7422 |
| タンパク質の説明: | Rabbit polyclonal antibody to PGRMC1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit |
| 分子量: | 21kDa; 22kD(Calculated). |
| ユニプロット: | O00264 |
| RRID: | AB_2839360 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7422, RRID:AB_2839360.
折りたたみ／展開
HPR6.6; Membrane associated progesterone receptor component 1; Membrane-associated progesterone receptor component 1; mPR; PGRC1_HUMAN; PGRMC; Pgrmc1; Progesterone binding protein; Progesterone receptor membrane component 1;
免疫原
A synthesized peptide derived from human PGRMC1, corresponding to a region within C-terminal amino acids.
- O00264 PGRC1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDDEPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVYSDEEEPKDESARKND
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs).
Microsome membrane>Single-pass membrane protein. Smooth endoplasmic reticulum membrane>Single-pass membrane protein.
Widely expressed, with highest expression in liver and kidney.
The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.
Belongs to the cytochrome b5 family. MAPR subfamily.
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