GSTP1 Antibody - #DF7462
(2)
(2)
| 製品: | GSTP1 Antibody |
| カタログ: | DF7462 |
| タンパク質の説明: | Rabbit polyclonal antibody to GSTP1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Rabbit, Dog, Xenopus |
| 分子量: | 23kDa; 23kD(Calculated). |
| ユニプロット: | P09211 |
| RRID: | AB_2839399 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7462, RRID:AB_2839399.
折りたたみ／展開
Deafness X linked 7; DFN7; FAEES3; Fatty acid ethyl ester synthase III; Glutathione S transferase pi 1; Glutathione S-transferase P; GST class-pi; GST3; Gstp1; GSTP1-1; GSTP1_HUMAN; GSTpi; PI;
免疫原
- P09211 GSTP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P09211 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y4 | Phosphorylation | P00533 (EGFR) | Uniprot |
| Y8 | Phosphorylation | P00533 (EGFR) | Uniprot |
| S28 | Phosphorylation | Uniprot | |
| K30 | Sumoylation | Uniprot | |
| S43 | Phosphorylation | P24723 (PRKCH) | Uniprot |
| K45 | Methylation | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| C48 | S-Nitrosylation | Uniprot | |
| Y50 | Phosphorylation | Uniprot | |
| K55 | Acetylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| T62 | Phosphorylation | Uniprot | |
| Y64 | Phosphorylation | Uniprot | |
| Y80 | Phosphorylation | Uniprot | |
| K82 | Methylation | Uniprot | |
| K82 | Sumoylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| K103 | Acetylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| Y109 | Phosphorylation | Uniprot | |
| T110 | Phosphorylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K121 | Acetylation | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| T132 | Phosphorylation | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| K141 | Methylation | Uniprot | |
| K141 | Sumoylation | Uniprot | |
| S185 | Phosphorylation | P24723 (PRKCH) , P17252 (PRKCA) , P17612 (PRKACA) | Uniprot |
| K189 | Acetylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| K191 | Acetylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| S196 | Phosphorylation | Uniprot | |
| Y199 | Phosphorylation | P00533 (EGFR) | Uniprot |
| K209 | Acetylation | Uniprot | |
| K209 | Methylation | Uniprot | |
| K209 | Ubiquitination | Uniprot |
研究背景
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Cytoplasm. Mitochondrion. Nucleus.
Note: The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Homodimer. Interacts with CDK5.
Belongs to the GST superfamily. Pi family.
研究領域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
· Human Diseases > Cancers: Specific types > Prostate cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.
· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - other enzymes.
参考文献
Application: WB Species: human Sample: GC cells
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