製品: NDUFB6 Antibody
カタログ: DF2213
タンパク質の説明: Rabbit polyclonal antibody to NDUFB6
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Xenopus
分子量: 15 kDa; 15kD(Calculated).
ユニプロット: O95139
RRID: AB_2839444

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Xenopus(82%)
クローナリティ:
Polyclonal
特異性:
NDUFB6 Antibody detects endogenous levels of total NDUFB6.
RRID:
AB_2839444
引用形式: Affinity Biosciences Cat# DF2213, RRID:AB_2839444.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B17; CI; CI B17; CI-B17; Complex I mitochondrial respiratory chain B17 subunit; Complex I-B17; Complex IB17; MGC13675; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; NADH ubiquinone oxidoreductase B17 subunit; NADH ubiquinone oxidoreductase beta subunit 6; NADH-ubiquinone oxidoreductase B17 subunit; NDUB6_HUMAN; NDUFB6;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
タンパク質配列:
MTGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPQKMGPMEKFWNKFLENKSPWRKMVHGVYKKSIFVFTHVLVPVWIIHYYMKYHVSEKPYGIVEKKSRIFPGDTILETGEVIPPMKEFPDQHH

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Xenopus
82
Bovine
73
Dog
73
Rabbit
73
Sheep
64
Chicken
64
Pig
55
Horse
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95139 基板として

Site PTM Type Enzyme
T2 Acetylation
T2 Phosphorylation
T5 Phosphorylation
K9 Ubiquitination
K24 Ubiquitination
S29 Phosphorylation
K49 Acetylation
K49 Ubiquitination
K54 Ubiquitination
S55 Phosphorylation
K66 Acetylation
K66 Ubiquitination
K67 Acetylation
K93 Ubiquitination
Y95 Phosphorylation
K100 Ubiquitination
T113 Phosphorylation

研究背景

機能:

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

細胞の位置付け:

Mitochondrion inner membrane>Single-pass membrane protein>Matrix side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Complex I is composed of 45 different subunits.

タンパク質ファミリー:

Belongs to the complex I NDUFB6 subunit family.

研究領域

· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).

· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.