ATP12A Antibody - #DF2223
| 製品: | ATP12A Antibody |
| カタログ: | DF2223 |
| タンパク質の説明: | Rabbit polyclonal antibody to ATP12A |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse |
| 予測: | Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 115kDa; 116kD(Calculated). |
| ユニプロット: | P54707 |
| RRID: | AB_2839454 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2223, RRID:AB_2839454.
折りたたみ／展開
ATP1AL1; ATPase H+/K+ transporting nongastric alpha polypeptide; ATPase Na+K+ transporting alpha-1 polypeptide-like; Hydrogen/potassium-exchanging ATPase 12A; Non-gastric H(+)/K(+) ATPase subunit alpha; Potassium-transporting ATPase alpha chain 2; Proton pump; Sodium/potassium ATPase alpha polypeptide-like;
免疫原
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
- P54707 AT12A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MHQKTPEIYSVELSGTKDIVKTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P54707 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T5 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| K42 | Acetylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| T101 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| T170 | Phosphorylation | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| K449 | Acetylation | Uniprot | |
| K459 | Acetylation | Uniprot | |
| K627 | Ubiquitination | Uniprot | |
| T632 | Phosphorylation | Uniprot | |
| T638 | Phosphorylation | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| K713 | Ubiquitination | Uniprot | |
| K788 | Ubiquitination | Uniprot | |
| K856 | Acetylation | Uniprot | |
| S985 | Phosphorylation | Uniprot | |
| Y1038 | Phosphorylation | Uniprot | |
| Y1039 | Phosphorylation | Uniprot |
研究背景
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
Membrane>Multi-pass membrane protein.
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level).
Composed of two subunits: alpha (catalytic) and beta.
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
研究領域
· Metabolism > Energy metabolism > Oxidative phosphorylation.
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