製品: SYF2 Antibody
カタログ: DF2224
タンパク質の説明: Rabbit polyclonal antibody to SYF2
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 28kDa; 29kD(Calculated).
ユニプロット: O95926
RRID: AB_2839455

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
SYF2 Antibody detects endogenous levels of total SYF2.
RRID:
AB_2839455
引用形式: Affinity Biosciences Cat# DF2224, RRID:AB_2839455.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CBPIN; CCNDBP1 interactor; CCNDBP1-interactor; DKFZp564O2082; fSAP29; Functional spliceosome associated protein 29; GCIP interacting protein p29; GCIPIP; NTC31; P29; Pre mRNA splicing factor SYF2; Pre-mRNA-splicing factor syf2; syf2; SYF2 homolog; SYF2 homolog RNA splicing factor (S. cerevisiae); SYF2 homolog RNA splicing factor; SYF2_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O95926 SYF2_HUMAN:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

タンパク質の説明:
May be involved in pre-mRNA splicing
タンパク質配列:
MAAIAASEVLVDSAEEGSLAAAAELAAQKREQRLRKFRELHLMRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELKEEEKKKECAARGEDYEKVKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYHRLTKQIKPDMETYERLREKHGEEFFPTSNSLLHGTHVPSTEEIDRMVIDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95926 基板として

Site PTM Type Enzyme
A2 Acetylation
S13 Phosphorylation
Y95 Phosphorylation
Y127 Phosphorylation
K143 Sumoylation
Y149 Phosphorylation
K155 Ubiquitination
Y196 Phosphorylation
Y210 Phosphorylation
Y226 Phosphorylation
K228 Acetylation
Y229 Phosphorylation
K234 Sumoylation
K234 Ubiquitination

研究背景

機能:

Involved in pre-mRNA splicing as component of the spliceosome.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

サブユニット構造:

Identified in the spliceosome C complex. Interacts with CCNDBP1.

タンパク質ファミリー:

Belongs to the SYF2 family.

研究領域

· Genetic Information Processing > Transcription > Spliceosome.

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