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製品説明

ソース:
Mouse
アプリケーション:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFB1868]
RRID:
AB_2833892
引用形式: Affinity Biosciences Cat# BF0657, RRID:AB_2833892.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ36569; MGC3245; Msi2; MSI2/HOXA9 fusion gene, included; MSI2H; MSI2H_HUMAN; Musashi 2; Musashi homolog 2; Musashi RNA binding protein 2; Musashi, Drosophila, homolog of, 2; Musashi-2; RNA binding protein Musashi homolog 2; RNA-binding protein Musashi homolog 2; WD 40 repeat protein MSI2;

免疫原

免疫原:

Purified recombinant fragment of human MSI2 expressed in E. Coli.

Uniprot:
遺伝子(ID):
発現特異性:
Q96DH6 MSI2H_HUMAN:

Ubiquitous; detected at low levels.

タンパク質配列:
MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGYH

PTMs - Q96DH6 基板として

Site PTM Type Enzyme
M1 Acetylation
S6 Phosphorylation
T9 Phosphorylation
S16 Phosphorylation
T32 Phosphorylation
S33 Phosphorylation
K43 Acetylation
K43 Ubiquitination
K59 Ubiquitination
S74 Phosphorylation
K77 Ubiquitination
K89 Ubiquitination
K94 Ubiquitination
K104 Ubiquitination
Y129 Phosphorylation
K135 Ubiquitination
K145 Ubiquitination
K166 Ubiquitination
K178 Ubiquitination
R197 Methylation
R199 Methylation
R201 Methylation
R228 Methylation
R261 Methylation

研究背景

機能:

RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

PTMs:

Phosphorylated.

細胞の位置付け:

Cytoplasm.
Note: Associated with polysomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous; detected at low levels.

タンパク質ファミリー:

Belongs to the Musashi family.

研究領域

· Genetic Information Processing > Translation > mRNA surveillance pathway.

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.