TTC19 Antibody - #DF2412
| 製品: | TTC19 Antibody |
| カタログ: | DF2412 |
| タンパク質の説明: | Rabbit polyclonal antibody to TTC19 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 35 kDa; 42kD(Calculated). |
| ユニプロット: | Q6DKK2 |
| RRID: | AB_2839618 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2412, RRID:AB_2839618.
折りたたみ／展開
2010204O13Rik; FLJ20343; MGC138312; MGC19520; mitochondrial; RIKEN cDNA 2810460C24; Tetratricopeptide repeat protein 19; TPR repeat protein 19; Ttc 19; TTC19; TTC19_HUMAN;
免疫原
- Q6DKK2 TTC19_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFRLLSWSLGRGFLRAAGRRCRGCSARLLPGLAGGPGPEVQVPPSRVAPHGRGPGLLPLLAALAWFSRPAAAEEEEQQGADGAAAEDGADEAEAEIIQLLKRAKLSIMKDEPEEAELILHDALRLAYQTDNKKAITYTYDLMANLAFIRGQLENAEQLFKATMSYLLGGGMKQEDNAIIEISLKLASIYAAQNRQEFAVAGYEFCISTLEEKIEREKELAEDIMSVEEKANTHLLLGMCLDACARYLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQINHPELHMVLSNLAAVLMHRERYTQAKEIYQEALKQAKLKKDEISVQHIREELAELSKKSRPLTNSVKL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6DKK2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K101 | Ubiquitination | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K346 | Ubiquitination | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| S377 | Phosphorylation | Uniprot |
研究背景
Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity.
Mitochondrion inner membrane.
Binds to the mature mitochondrial complex III dimer, after the incorporation of the Rieske protein UQCRFS1. Interacts with UQCRC1 and UQCRFS1 (By similarity). Interacts with ZFYVE26 and CHMP4B.
Belongs to the TTC19 family.
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