VSIG2 Antibody - #DF2446

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製品: VSIG2 Antibody
カタログ: DF2446
タンパク質の説明: Rabbit polyclonal antibody to VSIG2
アプリケーション: WB IHC
反応性: Human, Rat
予測: Horse, Sheep, Dog
分子量: 34 kDa; 34kD(Calculated).
ユニプロット: Q96IQ7
RRID: AB_2839652

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Horse(88%), Sheep(88%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
VSIG2 Antibody detects endogenous levels of total VSIG2.
RRID:
AB_2839652
引用形式: Affinity Biosciences Cat# DF2446, RRID:AB_2839652.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

2210413P10Rik; cortical thymocyte receptor (X. laevis CTX) like; Cortical thymocyte-like protein; CT-like protein; CTH; Ctm; CTXL; OTTHUMP00000197171; OTTHUMP00000197172; V set and immunoglobulin domain containing 2; V-set and immunoglobulin domain-containing protein 2; VSIG2; VSIG2_HUMAN;

免疫原

免疫原:
Uniprot:

Q96IQ7(VSIG2_HUMAN) >>Visit HPA database.

遺伝子(ID):
VSIG2(23584)
発現特異性:
Q96IQ7 VSIG2_HUMAN:

Highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung.

タンパク質配列:
MAELPGPFLCGALLGFLCLSGLAVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLREDAIAPGISEHTCMRADSSKGFLERPSSASTVTTTKSKLPMVV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
88
Sheep
88
Dog
88
Pig
0
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96IQ7 基板として

Site PTM Type Enzyme
S302 Phosphorylation
S303 Phosphorylation
T318 Phosphorylation
T319 Phosphorylation

研究背景

細胞の位置付け:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung.

参考文献

1). Key Candidate Genes–VSIG2 of Colon Cancer Identified by Weighted Gene Co-Expression Network Analysis. Cancer Management and Research, 2021 (PubMed: 34290531) [IF=3.3]

Application: IHC    Species: Human    Sample: cancer tissues

Figure 6 (A) The expression of VSIG2 in normal tissues. (B) The expression of VSIG2 in cancer tissues. (C) The expression of LC3 in cancer tissues.

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