製品: HSPA4L Antibody
カタログ: DF2503
タンパク質の説明: Rabbit polyclonal antibody to HSPA4L
アプリケーション: WB
反応性: Human, Mouse
予測: Bovine, Horse, Sheep, Rabbit, Dog
分子量: 94 kDa; 95kD(Calculated).
ユニプロット: O95757
RRID: AB_2839709

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Bovine(92%), Horse(92%), Sheep(92%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
HSPA4L Antibody detects endogenous levels of total HSPA4L.
RRID:
AB_2839709
引用形式: Affinity Biosciences Cat# DF2503, RRID:AB_2839709.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

94kDa; AI461691; APG 1; Heat shock 70kDa protein 4 like; MGC117843; MGC187594; Osmotic stress protein 94; Osp94; OTTMUSP00000027739;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVFCKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEGHQKCHAEHTPEEEIDHTGAKTKSAVSDKQDRLNQTLKKGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGPMDGQSGTETKSDSTKDSSQHTKSSGEMEVD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
100
Horse
92
Bovine
92
Sheep
92
Chicken
75
Zebrafish
56
Pig
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95757 基板として

Site PTM Type Enzyme
S20 Phosphorylation
T25 Phosphorylation
R33 Methylation
K53 Ubiquitination
S54 Phosphorylation
K68 Ubiquitination
S74 Phosphorylation
R86 Methylation
K93 Ubiquitination
K102 Ubiquitination
K126 Ubiquitination
K194 Ubiquitination
K219 Acetylation
K221 Acetylation
K221 Ubiquitination
Y230 Phosphorylation
K249 Ubiquitination
K257 Ubiquitination
R265 Methylation
K272 Acetylation
K272 Ubiquitination
K274 Acetylation
K275 Ubiquitination
K351 Ubiquitination
K356 Ubiquitination
K360 Ubiquitination
T365 Phosphorylation
S384 Phosphorylation
K388 Methylation
K388 Ubiquitination
C417 S-Nitrosylation
C421 S-Nitrosylation
K422 Ubiquitination
K430 Ubiquitination
K437 Ubiquitination
K477 Ubiquitination
S508 Phosphorylation
T514 Phosphorylation
S517 Phosphorylation
C540 S-Nitrosylation
T545 Phosphorylation
T571 Phosphorylation
K573 Ubiquitination
S579 Phosphorylation
S587 Phosphorylation
C589 S-Nitrosylation
S599 Phosphorylation
Y600 Phosphorylation
K612 Ubiquitination
K621 Ubiquitination
Y627 Phosphorylation
K641 Ubiquitination
Y663 Phosphorylation
K671 Ubiquitination
Y684 Phosphorylation
Y692 Phosphorylation
Y726 Phosphorylation
K736 Ubiquitination
K739 Ubiquitination
K757 Ubiquitination
T761 Phosphorylation
K788 Ubiquitination
S814 Phosphorylation

研究背景

機能:

Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.

細胞の位置付け:

Cytoplasm. Nucleus.
Note: May translocate to the nucleus after heat shock.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the heat shock protein 70 family.

研究領域

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum.   (View pathway)

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