PDCD1LG2 Antibody - #DF2561
| 製品: | PDCD1LG2 Antibody |
| カタログ: | DF2561 |
| タンパク質の説明: | Rabbit polyclonal antibody to PDCD1LG2 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 予測: | Pig, Horse, Dog |
| 分子量: | 31 kDa; 31kD(Calculated). |
| ユニプロット: | Q9BQ51 |
| RRID: | AB_2839767 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2561, RRID:AB_2839767.
折りたたみ／展開
B7 dendritic cell molecule; B7-DC; B7DC; bA574F11.2; Btdc; Butyrophilin B7 DC; Butyrophilin B7-DC; Butyrophilin B7DC; CD 273; CD273; CD273 antigen; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD-1 ligand 2; PD-L2; PD1 ligand 2; PD1L2_HUMAN; PDCD 1 ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; PDL 2; PDL2; Programmed cell death 1 ligand 2; Programmed death ligand 2;
免疫原
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
- Q9BQ51 PD1L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BQ51 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y114 | Phosphorylation | Uniprot | |
| T116 | Phosphorylation | Uniprot | |
| T128 | Phosphorylation | Uniprot | |
| S159 | Phosphorylation | Uniprot | |
| S165 | Phosphorylation | Uniprot | |
| S167 | Phosphorylation | Uniprot |
研究背景
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
Secreted.
Endomembrane system>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Interacts with PDCD1.
Belongs to the immunoglobulin superfamily. BTN/MOG family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
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