製品: BCL7B Antibody
カタログ: DF2586
タンパク質の説明: Rabbit polyclonal antibody to BCL7B
アプリケーション: WB
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 22 kDa; 22kD(Calculated).
ユニプロット: Q9BQE9
RRID: AB_2839792

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(100%), Horse(83%), Sheep(100%), Rabbit(92%), Dog(100%), Chicken(83%)
クローナリティ:
Polyclonal
特異性:
BCL7B Antibody detects endogenous levels of total BCL7B.
RRID:
AB_2839792
引用形式: Affinity Biosciences Cat# DF2586, RRID:AB_2839792.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; B-cell CLL/lymphoma 7 protein family member B; BCL 7B; BCL7B; BCL7B_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9BQE9 BCL7B_HUMAN:

Ubiquitous.

タンパク質の説明:
May play a role in lung tumor development or progression.
タンパク質配列:
MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
92
Horse
83
Chicken
83
Xenopus
67
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BQE9 基板として

Site PTM Type Enzyme
K27 Ubiquitination
K34 Ubiquitination
T41 Phosphorylation
S107 Phosphorylation
S108 Phosphorylation
T109 Phosphorylation
S112 Phosphorylation
S114 Phosphorylation
S118 Phosphorylation
S120 Phosphorylation
S122 Phosphorylation
T126 Phosphorylation
S127 Phosphorylation
T131 Phosphorylation
S134 Phosphorylation
S180 Phosphorylation
K186 Ubiquitination
C189 S-Nitrosylation
T194 Phosphorylation
S200 Phosphorylation

研究背景

機能:

Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).

組織特異性:

Ubiquitous.

タンパク質ファミリー:

Belongs to the BCL7 family.

Restrictive clause

 

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