CANT1 Antibody - #DF2590
| 製品: | CANT1 Antibody |
| カタログ: | DF2590 |
| タンパク質の説明: | Rabbit polyclonal antibody to CANT1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 45 kDa; 45kD(Calculated). |
| ユニプロット: | Q8WVQ1 |
| RRID: | AB_2839796 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2590, RRID:AB_2839796.
折りたたみ／展開
Apyrase; Apyrase homolog; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase; Calcium activated nucleotidase 1; CANT 1; CANT1; CANT1_HUMAN; Putative MAPK activating protein PM09; Putative MAPK-activating protein PM09; Putative NF kappa B activating protein 107; Putative NF-kappa-B-activating protein 107; SCAN 1; SCAN-1; SHAPY; Soluble Ca activated nucleotidase isozyme 1; Soluble calcium activated nucleotidase 1; Soluble calcium activated nucleotidase SCAN 1; Soluble calcium-activated nucleotidase 1;
免疫原
- Q8WVQ1 CANT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPVQLSEHPEWNESMHSLRISVGGLPVLASMTKAADPRFRPRWKVILTFFVGAAILWLLCSHRPAPGRPPTHNAHNWRLGQAPANWYNDTYPLSPPQRTPAGIRYRIAVIADLDTESRAQEENTWFSYLKKGYLTLSDSGDKVAVEWDKDHGVLESHLAEKGRGMELSDLIVFNGKLYSVDDRTGVVYQIEGSKAVPWVILSDGDGTVEKGFKAEWLAVKDERLYVGGLGKEWTTTTGDVVNENPEWVKVVGYKGSVDHENWVSNYNALRAAAGIQPPGYLIHESACWSDTLQRWFFLPRRASQERYSEKDDERKGANLLLSASPDFGDIAVSHVGAVVPTHGFSSFKFIPNTDDQIIVALKSEEDSGRVASYIMAFTLDGRFLLPETKIGSVKYEGIEFI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WVQ1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S17 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| Y133 | Phosphorylation | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| K161 | Ubiquitination | Uniprot | |
| S202 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot |
研究背景
Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
N-glycosylated.
Endoplasmic reticulum membrane>Single-pass type II membrane protein. Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein. Cell membrane.
Note: Processed form: Secreted.
Widely expressed.
Monomer. Homodimer; dimerization is Ca(2+)-dependent. Homodimer; disulfide-linked (membrane form).
Belongs to the apyrase family.
研究領域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
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