BAG2 Antibody - #DF2650
| 製品: | BAG2 Antibody |
| カタログ: | DF2650 |
| タンパク質の説明: | Rabbit polyclonal antibody to BAG2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Bovine, Sheep, Rabbit, Dog |
| 分子量: | 24 kDa; 24kD(Calculated). |
| ユニプロット: | O95816 |
| RRID: | AB_2839856 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2650, RRID:AB_2839856.
折りたたみ／展開
BAG 2; BAG family molecular chaperone regulator 2; BAG-2; BAG-family molecular chaperone regulator-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; BCL2-associated athanogene 2; dJ417I1.2 (BAG family molecular chaperone regulator 2); dJ417I1.2; KIAA0576; MGC149462; OTTHUMP00000016668;
免疫原
- O95816 BAG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQAKINAKANEGRFCRSSSMADRSSRLLESLDQLELRVEALREAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQQESLKHATRIIDEVVNKFLDDLGNAKSHLMSLYSACSSEVPHGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIENSDKAIKLLEHSKGAGSKTLQQNAESRFN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95816 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| K9 | Ubiquitination | Uniprot | |
| S20 | Phosphorylation | P49137 (MAPKAPK2) | Uniprot |
| S31 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| K111 | Acetylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| S133 | Phosphorylation | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| Y139 | Phosphorylation | Uniprot | |
| S140 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S144 | Phosphorylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| C162 | S-Nitrosylation | Uniprot | |
| K168 | Acetylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| K169 | Acetylation | Uniprot | |
| T176 | Phosphorylation | Uniprot | |
| K186 | Acetylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| K195 | Ubiquitination | Uniprot | |
| K200 | Ubiquitination | Uniprot | |
| T201 | Phosphorylation | Uniprot |
研究背景
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.
Binds to the ATPase domain of HSP/HSC70 chaperones. May interact with NWD1. Interacts with HSPA1A (via NBD), HSPA1B (via NBD) and HSPA8.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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