PRKD3 Antibody - #DF2674
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2674, RRID:AB_2839880.
折りたたみ／展開
EPK 2; EPK2; KPCD3_HUMAN; nPKC nu; nPKC-nu; nPKCnu; nu; PKCnu; PKD 3; PKD3; PRK D3; PRKCN; PRKD 3; Prkd3; Protein kinase C; Protein kinase C nu; Protein kinase C nu type; Protein kinase D3; Protein kinase EPK 2; Protein kinase EPK2; Serine threonine protein kinase; Serine/threonine protein kinase D3; Serine/threonine-protein kinase D3;
免疫原
- O94806 KPCD3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNPVLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHESDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O94806 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| S30 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| T360 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| S391 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| S406 | Phosphorylation | Uniprot | |
| K408 | Ubiquitination | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| T446 | Phosphorylation | Uniprot | |
| Y456 | Phosphorylation | Uniprot | |
| S463 | Phosphorylation | Uniprot | |
| T535 | Phosphorylation | Uniprot | |
| S543 | Phosphorylation | Uniprot | |
| K605 | Ubiquitination | Uniprot | |
| K615 | Ubiquitination | Uniprot | |
| K730 | Ubiquitination | Uniprot | |
| S731 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| S735 | Phosphorylation | Uniprot | |
| T739 | Phosphorylation | Uniprot | |
| Y742 | Phosphorylation | Uniprot | |
| K816 | Ubiquitination | Uniprot |
PTMs - O94806 酵素として
| Substrate | Site | Source |
|---|---|---|
| P49840 (GSK3A) | S21 | Uniprot |
| P49841 (GSK3B) | S9 | Uniprot |
| Q04206 (RELA) | S276 | Uniprot |
| Q04206 (RELA) | S536 | Uniprot |
| Q15139 (PRKD1) | S738 | Uniprot |
| Q15139 (PRKD1) | S742 | Uniprot |
| Q9BST9 (RTKN) | S448 | Uniprot |
| Q9NRA0 (SPHK2) | S419 | Uniprot |
| Q9NRA0 (SPHK2) | S421 | Uniprot |
| Q9UQL6 (HDAC5) | S498 | Uniprot |
| Q9Y2X7 (GIT1) | S46 | Uniprot |
研究背景
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Cytoplasm. Membrane.
Note: Translocation to the cell membrane is required for kinase activation.
Ubiquitous.
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
研究領域
· Environmental Information Processing > Signal transduction > Rap1 signaling pathway. (View pathway)
· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.
Restrictive clause
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For Research Use Only.
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