PKN3 Antibody - #DF2678
| 製品: | PKN3 Antibody |
| カタログ: | DF2678 |
| タンパク質の説明: | Rabbit polyclonal antibody to PKN3 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 99kDa,112kDa,104kDa; 99kD(Calculated). |
| ユニプロット: | Q6P5Z2 |
| RRID: | AB_2839884 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2678, RRID:AB_2839884.
折りたたみ／展開
pkn3; PKN3_HUMAN; PKNBETA; Protein kinase C related kinase 3; Protein kinase N3; Protein kinase PKN beta; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; RP11-545E17.1; Serine/threonine protein kinase N3; Serine/threonine-protein kinase N3;
免疫原
Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
- Q6P5Z2 PKN3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKVKQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLLEQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSPAAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVIPLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVIERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRTPTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTRRGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDEIESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLCGPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6P5Z2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K20 | Ubiquitination | Uniprot | |
| K29 | Ubiquitination | Uniprot | |
| R58 | Methylation | Uniprot | |
| T135 | Phosphorylation | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K155 | Ubiquitination | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K273 | Ubiquitination | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| S466 | Phosphorylation | Uniprot | |
| S472 | Phosphorylation | Uniprot | |
| T480 | Phosphorylation | Uniprot | |
| S488 | Phosphorylation | Uniprot | |
| T492 | Phosphorylation | Uniprot | |
| S494 | Phosphorylation | Uniprot | |
| K499 | Ubiquitination | Uniprot | |
| T508 | Phosphorylation | Uniprot | |
| K512 | Ubiquitination | Uniprot | |
| T523 | Phosphorylation | Uniprot | |
| S524 | Phosphorylation | Uniprot | |
| T527 | Phosphorylation | Uniprot | |
| S544 | Phosphorylation | Q6P5Z2 (PKN3) | Uniprot |
| S548 | Phosphorylation | Uniprot | |
| T550 | Phosphorylation | Q6P5Z2 (PKN3) | Uniprot |
| K583 | Acetylation | Uniprot | |
| K583 | Ubiquitination | Uniprot | |
| K588 | Ubiquitination | Uniprot | |
| K592 | Ubiquitination | Uniprot | |
| K686 | Ubiquitination | Uniprot | |
| T716 | Phosphorylation | Uniprot | |
| S717 | Phosphorylation | Uniprot | |
| T718 | Phosphorylation | Uniprot | |
| T722 | Phosphorylation | Uniprot | |
| K796 | Ubiquitination | Uniprot | |
| K813 | Ubiquitination | Uniprot | |
| T820 | Phosphorylation | Uniprot | |
| T860 | Phosphorylation | Uniprot |
PTMs - Q6P5Z2 酵素として
研究背景
Contributes to invasiveness in malignant prostate cancer.
Autophosphorylated.
Nucleus. Cytoplasm>Perinuclear region.
Note: Nuclear and perinuclear Golgi region.
Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
The C1 domain does not bind the diacylglycerol (DAG).
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
研究領域
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Salmonella infection.
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