Cyclin G Antibody - #AF0145
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0145, RRID:AB_2833327.
折りたたみ／展開
CCNG 1; CCNG; CCNG1; CCNG1_HUMAN; CYCG1; Cyclin G; Cyclin G1; Cyclin-G; Cyclin-G1;
免疫原
- P51959 CCNG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P51959 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K12 | Acetylation | Uniprot | |
| S25 | Phosphorylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| T48 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K247 | Ubiquitination | Uniprot |
研究背景
May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Nucleus.
Note: DNA replication foci after DNA damage.
High levels in skeletal muscle, ovary, kidney and colon.
Belongs to the cyclin family. Cyclin G subfamily.
研究領域
· Cellular Processes > Cell growth and death > p53 signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > MicroRNAs in cancer.
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