製品: GPR92/GPR93 Antibody
カタログ: DF2774
タンパク質の説明: Rabbit polyclonal antibody to GPR92/GPR93
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Bovine
分子量: Predicted band size : 41 kDa,Observed band size : 41 kDa; 41kD(Calculated).
ユニプロット: Q9H1C0
RRID: AB_2839980

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Bovine(80%)
クローナリティ:
Polyclonal
特異性:
GPR92/GPR93 Antibody detects endogenous levels of total GPR92/GPR93.
RRID:
AB_2839980
引用形式: Affinity Biosciences Cat# DF2774, RRID:AB_2839980.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

G protein coupled receptor 92; G-protein coupled receptor 92; G-protein coupled receptor 93; GPR 92; GPR 93; GPR92; GPR93; KPG 010; LPA receptor 5; LPA-5; Lpar5; LPAR5_HUMAN; Lysophosphatidic acid receptor 5; Probable G protein coupled receptor 92; Putative G protein coupled receptor 92;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9H1C0 LPAR5_HUMAN:

Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.

タンパク質の説明:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
タンパク質配列:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
80
Pig
0
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H1C0 基板として

Site PTM Type Enzyme
Y29 Phosphorylation
S268 Phosphorylation
S332 Phosphorylation

研究背景

機能:

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

研究領域

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

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For Research Use Only.
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