GRPR Antibody - #DF2815
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| 製品: | GRPR Antibody |
| カタログ: | DF2815 |
| タンパク質の説明: | Rabbit polyclonal antibody to GRPR |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 53 kDa; 43kD(Calculated). |
| ユニプロット: | P30550 |
| RRID: | AB_2840021 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2815, RRID:AB_2840021.
折りたたみ／展開
BB2; Bombesin BB2 receptor; bombesin receptor 2; Gastrin Releasing Peptide Receptor; Gastrin-releasing peptide receptor; GRP preferring bombesin receptor; GRP R; GRP-preferring bombesin receptor; GRP-R; Grp/bombesin receptor; Grpr; GRPR_HUMAN;
免疫原
Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
- P30550 GRPR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSLKSTNPSVATFSLINGNICHERYV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P30550 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S354 | Phosphorylation | Uniprot | |
| K362 | Acetylation | Uniprot |
研究背景
Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).
Cell membrane>Multi-pass membrane protein.
Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
参考文献
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