FLI1 Antibody - #AF0161
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0161, RRID:AB_2833342.
折りたたみ／展開
ERGB transcription factor; Ewing Sarcoma breakpoint region 2; EWSR 2; EWSR2; FLI 1; FLI 1 proto oncogene; Fli-1 proto-oncogene, ETS transcription factor; FLI1; FLI1 EWS fusion gene; FLI1 proto oncogene; FLI1_HUMAN; Friend leukemia integration 1 (FLI1) transcription factor; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Sarcoma breakpoint region 2 (EWSR2); SIC 1; SIC1; Transcription factor ERGB; Viral integration region FLI1; Viral integration region FLI1, mouse, homolog of;
免疫原
- Q01543 FLI1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQPVRVNVKREYDHMNGSRESPVDCSVSKCSKLVGGGESNPMNYNSYMDEKNGPPPPNMTTNERRVIVPADPTLWTQEHVRQWLEWAIKEYSLMEIDTSFFQNMDGKELCKMNKEDFLRATTLYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLSVKEDPSYDSVRRGAWGNNMNSGLNKSPPLGGAQTISKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPTESSMYKYPSDISYMPSYHAHQQKVNFVPPHPSSMPVTSSSFFGAASQYWTSPTGGIYPNPNVPRHPNTHVPSHLGSYY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q01543 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| T35 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| Y42 | Phosphorylation | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| K67 | Sumoylation | Uniprot | |
| Y70 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| S79 | Phosphorylation | Uniprot | |
| S86 | Phosphorylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S89 | Phosphorylation | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| Y222 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| K240 | Acetylation | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| S241 | Phosphorylation | Uniprot | |
| K252 | Acetylation | Uniprot | |
| Y263 | Phosphorylation | Uniprot | |
| T312 | Phosphorylation | Q05655 (PRKCD) | Uniprot |
| K325 | Ubiquitination | Uniprot | |
| Y332 | Phosphorylation | Uniprot | |
| K334 | Ubiquitination | Uniprot | |
| K350 | Ubiquitination | Uniprot | |
| K380 | Acetylation | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| K397 | Acetylation | Uniprot | |
| R438 | Methylation | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| Y451 | Phosphorylation | Uniprot | |
| Y452 | Phosphorylation | Uniprot |
研究背景
Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
Nucleus.
Can form homodimers or heterodimers with ETV6/TEL1.
Belongs to the ETS family.
研究領域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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