PDZD2 Antibody - #AF0318
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0318, RRID:AB_2834170.
折りたたみ/展開
Activated in prostate cancer protein; AIPC; KIAA0300; PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain containing protein 2; PDZ domain containing protein 3; PDZK 3; PIN1; Plakophilin related armadillo repeat protein interacting PDZ protein like;
免疫原
- O15018 PDZD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPITQDNAVLHLPLLYQWLQNSLQEGGDGPEQRLCQAAIQKLQEYIQLNFAVDESTVPPDHSPPEMEICTVYLTKELGDTETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKHKAHSTYNGNSSNSSEPGETPTLELGDRTAKKGKRTRKFGVISRPPANKAPEESKGSAGCEVSSDPSTELENGPDPELGNGHVFQLENGPDSLKEVAGPHLERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSSWTDNEDQEADGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSNKIKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEVSRDGRKHSLPQLLDSSSASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSPSLTPCSTPTHMSRSASPNFNTSGGASAGGSDEGSSSSLGRKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEANSSPGLGTPLKSPSLAKKDSLISESELSQYFAHDVPGPLSDFMVAGSEDEDHPGSGCSTSEEGSLPPSTSTHKEPGKPRANSLVTLGSHRASGLFHKQVTVARQASLPGSPQALRNPLLRQRKVGCYDANDASDEEEFDREGDCISLPGALPGPIRPLSEDDPRRVSISSSKGMDVHNQEERPRKTLVSKAISAPLLGSSVDLEESIPEGMVDAASYAANLTDSAEAPKGSPGSWWKKELSGSSSAPKLEYTVRTDTQSPTNTGSPSSPQQKSEGLGSRHRPVARVSPHCKRSEAEAKPSGSQTVNLTGRANDPCDLDSRVQATSVKVTVAGFQPGGAVEKESLGKLTTGDACVSTSCELASALSHLDASHLTENLPKAASELGQQPMTELDSSSDLISSPGKKGAAHPDPSKTSVDTGQVSRPENPSQPASPRVTKCKARSPVRLPHEGSPSPGEKAAAPPDYSKTRSASETSTPHNTRRVAALRGAGPGAEGMTPAGAVLPGDPLTSQEQRQGAPGNHSKALEMTGIHAPESSQEPSLLEGADSVSSRAPQASLSMLPSTDNTKEACGHVSGHCCPGGSRESPVTDIDSFIKELDASAARSPSSQTGDSGSQEGSAQGHPPAGAGGGSSCRAEPVPGGQTSSPRRAWAAGAPAYPQWASQPSVLDSINPDKHFTVNKNFLSNYSRNFSSFHEDSTSLSGLGDSTEPSLSSMYGDAEDSSSDPESLTEAPRASARDGWSPPRSRVSLHKEDPSESEEEQIEICSTRGCPNPPSSPAHLPTQAAICPASAKVLSLKYSTPRESVASPREKAACLPGSYTSGPDSSQPSSLLEMSSQEHETHADISTSQNHRPSCAEETTEVTSASSAMENSPLSKVARHFHSPPIILSSPNMVNGLEHDLLDDETLNQYETSINAAASLSSFSVDVPKNGESVLENLHISESQDLDDLLQKPKMIARRPIMAWFKEINKHNQGTHLRSKTEKEQPLMPARSPDSKIQMVSSSQKKGVTVPHSPPQPKTNLENKDLSKKSPAEMLLTNGQKAKCGPKLKRLSLKGKAKVNSEAPAANAVKAGGTDHRKPLISPQTSHKTLSKAVSQRLHVADHEDPDRNTTAAPRSPQCVLESKPPLATSGPLKPSVSDTSIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAPRADSGPVSPAASRNGMSVAGNRQSEPRLASHVAADTAQPRPTGEKGGNIMASDRLERTNQLKIVEISAEAVSETVCGNKPAESDRRGGCLAQGNCQEKSEIRLYRQVAESSTSHPSSLPSHASQAEQEMSRSFSMAKLASSSSSLQTAIRKAEYSQGKSSLMSDSRGVPRNSIPGGPSGEDHLYFTPRPATRTYSMPAQFSSHFGREGHPPHSLGRSRDSQVPVTSSVVPEAKASRGGLPSLANGQGIYSVKPLLDTSRNLPATDEGDIISVQETSCLVTDKIKVTRRHYCYEQNWPHESTSFFSVKQRIKSFENLANADRPVAKSGASPFLSVSSKPPIGRRSSGSIVSGSLGHPGDAAARLLRRSLSSCSENQSEAGTLLPQMAKSPSIMTLTISRQNPPETSSKGSDSELKKSLGPLGIPTPTMTLASPVKRNKSSVRHTQPSPVSRSKLQELRALSMPDLDKLCSEDYSAGPSAVLFKTELEITPRRSPGPPAGGVSCPEKGGNRACPGGSGPKTSAAETPSSASDTGEAAQDLPFRRSWSVNLDQLLVSAGDQQRLQSVLSSVGSKSTILTLIQEAKAQSENEEDVCFIVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNGASLAGLAHGNVLKVLHQAQLHKDALVVIKKGMDQPRPSARQEPPTANGKGLLSRKTIPLEPGIGRSVAVHDALCVEVLKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNIMKSVPEGPVQLLIRKHRNSS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15018 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T200 | Phosphorylation | Uniprot | |
T209 | Phosphorylation | Uniprot | |
R283 | Methylation | Uniprot | |
R288 | Methylation | Uniprot | |
S304 | Phosphorylation | Uniprot | |
S320 | Phosphorylation | Uniprot | |
S421 | Phosphorylation | Uniprot | |
S506 | Phosphorylation | Uniprot | |
S514 | Phosphorylation | Uniprot | |
S536 | Phosphorylation | Uniprot | |
S543 | Phosphorylation | Uniprot | |
Y557 | Phosphorylation | Uniprot | |
S568 | Phosphorylation | Uniprot | |
S702 | Phosphorylation | Uniprot | |
S710 | Phosphorylation | Uniprot | |
T831 | Phosphorylation | Uniprot | |
S840 | Phosphorylation | Uniprot | |
T846 | Phosphorylation | Uniprot | |
S850 | Phosphorylation | Uniprot | |
S920 | Phosphorylation | Uniprot | |
S944 | Phosphorylation | Uniprot | |
S948 | Phosphorylation | Uniprot | |
S1005 | Phosphorylation | Uniprot | |
T1024 | Phosphorylation | Uniprot | |
S1031 | Phosphorylation | Uniprot | |
T1090 | Phosphorylation | Uniprot | |
T1093 | Phosphorylation | Uniprot | |
S1125 | Phosphorylation | Uniprot | |
T1142 | Phosphorylation | Uniprot | |
T1146 | Phosphorylation | Uniprot | |
S1157 | Phosphorylation | Uniprot | |
K1242 | Ubiquitination | Uniprot | |
S1250 | Phosphorylation | Uniprot | |
S1270 | Phosphorylation | Uniprot | |
S1280 | Phosphorylation | Uniprot | |
S1307 | Phosphorylation | Uniprot | |
S1309 | Phosphorylation | Uniprot | |
S1437 | Phosphorylation | Uniprot | |
S1578 | Phosphorylation | Uniprot | |
S1592 | Phosphorylation | Uniprot | |
S1594 | Phosphorylation | Uniprot | |
S1636 | Phosphorylation | Uniprot | |
T1637 | Phosphorylation | Uniprot | |
S1770 | Phosphorylation | Uniprot | |
K1820 | Ubiquitination | Uniprot | |
S1829 | Phosphorylation | Uniprot | |
S1850 | Phosphorylation | Uniprot | |
S1898 | Phosphorylation | Uniprot | |
S1919 | Phosphorylation | Uniprot | |
S1953 | Phosphorylation | Uniprot | |
S1960 | Phosphorylation | Uniprot | |
T1966 | Phosphorylation | Uniprot | |
S1967 | Phosphorylation | Uniprot | |
S2037 | Phosphorylation | Uniprot | |
Y2133 | Phosphorylation | Uniprot | |
S2142 | Phosphorylation | Uniprot | |
S2159 | Phosphorylation | Uniprot | |
S2189 | Phosphorylation | Uniprot | |
S2224 | Phosphorylation | Uniprot | |
S2246 | Phosphorylation | Uniprot | |
S2341 | Phosphorylation | Uniprot | |
S2374 | Phosphorylation | Uniprot | |
S2376 | Phosphorylation | Uniprot | |
S2396 | Phosphorylation | Uniprot | |
T2409 | Phosphorylation | Uniprot | |
S2417 | Phosphorylation | Uniprot | |
S2419 | Phosphorylation | Uniprot | |
T2422 | Phosphorylation | Uniprot | |
K2436 | Acetylation | Uniprot | |
S2438 | Phosphorylation | Uniprot | |
S2440 | Phosphorylation | Uniprot | |
K2444 | Acetylation | Uniprot | |
S2445 | Phosphorylation | Uniprot | |
T2453 | Phosphorylation | Uniprot | |
T2455 | Phosphorylation | Uniprot | |
S2460 | Phosphorylation | Uniprot | |
S2467 | Phosphorylation | Uniprot | |
T2472 | Phosphorylation | Uniprot | |
S2475 | Phosphorylation | Uniprot | |
S2478 | Phosphorylation | Uniprot | |
S2480 | Phosphorylation | Uniprot | |
S2489 | Phosphorylation | Uniprot | |
S2521 | Phosphorylation | Uniprot | |
S2530 | Phosphorylation | Uniprot | |
S2544 | Phosphorylation | Uniprot |
研究背景
A secreted form is produced by caspase-mediated proteolytic cleavage.
Nucleus. Cytoplasm. Endoplasmic reticulum.
Note: At cell-cell contacts in lung epithelial cells.
Secreted.
Isoform 2 is expressed (at protein level) in prostate and many prostate tumors.
Interacts with SCN10A, CTNND2 and PKP4.
参考文献
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